Thrombotic Obstruction in Hemodialysis Catheters

Thrombotic Obstruction in Hemodialysis Catheters: Urgent Evidence for Vascular Nursing

Thrombotic dysfunction in hemodialysis catheters represents a significant burden in clinical practice. A recent systematic review reports that the incidence of thrombosis in hemodialysis catheters ranges from 12% to 52%, depending on follow-up duration and clinical context.

From a pathophysiological perspective, the classic triad of endothelial injury + turbulent flow/stasis + hypercoagulable state is amplified in the catheter setting: biofilm formation, catheter material, and interdialytic stasis promote fibrin deposition and thrombus formation.

 

Nursing-oriented diagnosis:

  • Verify that blood flow (Qb) meets minimum standards and observe free backflow without resistance.

  • Exclude kinking, clamping, or catheter malposition (possible after patient repositioning).

  • Check connections, clamps, catheter pathway, and possible precipitates/proteins that may compromise the catheter lumen.

  • If suspicion persists after these steps, request diagnostic imaging (Doppler ultrasound) to rule out thrombosis.

 

Warning signs requiring escalation:

  • Sudden pain or edema in the limb with the catheter.

  • Fever without another evident source or signs of sepsis.

  • Complete inability to aspirate or infuse through the catheter.

 

Key readings:

  • López-Rubio M, et al. “A Comprehensive Review of Catheter-Related Thrombosis.” J Clin Med. 2024;13(24):7818.

  • Smit JM, et al. “Incidence of catheter-related thrombosis and its determinants in critically ill patients.” Thrombosis Research. 2024; S0049-3848(24)00200-7.

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